Activating STAT3 Gene Mutation

**Semantic type:** Cell or Molecular Dysfunction

**Definition:** A mutation in the STAT3 gene that results in an increase in cytokine-related function. STAT3 mutations of this type are associated with infantile-onset multisystem autoimmune disease.

**Synonyms:** - Activating STAT3 Mutation - STAT-3 GOF - STAT3 Activating Gene Mutation - STAT3 Activating Mutation - STAT3 Gain of Function - STAT3 Gain of Function Gene Mutation - STAT3 Gain of Function Mutation - STAT3 gain of function