SORL1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human SORL1 wild-type allele is located within 11q23.2-q24.2 and is approximately 182 kb in length. This allele, which encodes sortilin-related receptor protein, plays a role in both intracellular protein sorting and endocytosis of lipoproteins and enzymes. Mutation of the gene may be associated with Alzheimer disease.

**Synonyms:** - C11orf32 - Chromosome 11 Open Reading Frame 32 Gene - LR11 - LRP9 - SORLA - SorLA-1 - Sortilin-Related Receptor, L(DLR Class) A Repeats Containing wt Allele - Sortilin-Related Receptor, L(DLR Class) A Repeats-Containing Gene - gp250