ZFTA wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human ZFTA wild-type allele is located in the vicinity of 11q13.1 and is approximately 9 kb in length. This allele, which encodes zinc finger translocation-associated protein, may play a role in transcriptional regulation. A chromosomal aberration, t(11;16)(q13;p13), involving this gene and the MRTFB (MKL2) gene may be associated with chondroid lipomas. A chromosomal aberration involving chromothripsis of the long arm of chromosome 11 causes fusions of this gene and the RELA gene and is associated with more than two-thirds of supratentorial ependymomas.

**Synonyms:** - C11orf95 - Chromosome 11 Open Reading Frame 95 Gene - MGC3032 - Zinc Finger Translocation Associated wt Allele