GP1BA wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human GP1BA wild-type allele is located in the vicinity of 17p13.2 and is approximately 3 kb in length. This allele, which encodes platelet glycoprotein Ib alpha chain protein, is involved in the regulation of blood coagulation. Mutation of the gene is associated with Bernard-Soulier syndrome type A1 and platelet-type von Willebrand disease and with increased susceptibility to nonarteritic anterior ischemic optic neuropathy.

**Synonyms:** - BDPLT1 - BDPLT3 - BSS - CD42B - CD42b-alpha - DBPLT3 - GP Ib, Alpha Subunit Gene - GP1B - GPIbA - GPIbalpha - Glycoprotein Ib (Platelet), Alpha Polypeptide Gene - Glycoprotein Ib Platelet Alpha Subunit wt Allele - Glycoprotein Ib, Platelet, Alpha Polypeptide Gene - Platelet Glycoprotein Ib, Alpha Polypeptide Gene - VWDP