ACTN4 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human ACTN4 wild-type allele is located in the vicinity of 19q13 and is approximately 84 kb in length. This allele, which encodes alpha-actinin-4 protein, is involved in crosslinking actin to other cellular proteins. Mutations in this gene are associated with focal segmental glomerulosclerosis.

**Synonyms:** - ACTININ-4 - Actinin Alpha 4 wt Allele - Actinin, Alpha 4 Gene - Actinin, Alpha-4 Gene - FSGS - FSGS1 - Focal Segmental Glomerulosclerosis 1 Gene