PRICKLE1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human PRICKLE1 wild-type allele is located in the vicinity of 12q12 and is approximately 134 kb in length. This allele, which encodes prickle-like protein 1, plays a role in the negative regulation of Wnt signaling and in embryonic development. Mutation of the gene is associated with progressive myoclonic epilepsy 1B.

**Synonyms:** - EPM1B - FLJ31937 - Prickle Homolog 1 (Drosophila) Gene - Prickle Planar Cell Polarity Protein 1 wt Allele - Prickle, Drosophila, Homolog of, 1 Gene - Prickle-Like 1 (Drosophila) Gene - RILP