ROBO2 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human ROBO2 wild-type allele is located in the vicinity of 3p12.3 and is approximately 1743 kb in length. This allele, which encodes roundabout homolog 2 protein, is involved in axon guidance, cell migration and ligand binding. Chromosomal anomalies, including t(Y;3)(p11;p12), that cause dominant-negative mutations in this gene are associated with vesicoureteral reflux.

**Synonyms:** - KIAA1568 - Roundabout (Axon Guidance Receptor, Drosophila) Homolog 2 Gene - Roundabout Guidance Receptor 2 wt Allele - Roundabout, Axon Guidance Receptor, Homolog 2 (Drosophila) Gene - Roundabout, Axon Guidance Receptor, Homolog 2 Gene - Roundabout, Drosophila, Homolog of, 2 Gene - SAX3 - SAX3, C. elegans, Homolog of, 2 Gene