ROBO3 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human ROBO3 wild-type allele is located in the vicinity of 11q24.2 and is approximately 16 kb in length. This allele, which encodes roundabout homolog 3 protein, plays a role in axon guidance and neurite outgrowth. Mutation of the gene is associated with horizontal gaze palsy with progressive scoliosis.

**Synonyms:** - FLJ21044 - HGPPS - HGPS - Horizontal Gaze Palsy With Progressive Scoliosis Gene - RB-Inhibiting Gene 1 - RBIG1 - RIG1 - Retinoblastoma Inhibiting Gene 1 - Roundabout (Axon Guidance Receptor, Drosophila) Homolog 3 Gene - Roundabout Guidance Receptor 3 wt Allele - Roundabout, Axon Guidance Receptor, Homolog 3 (Drosophila) Gene - Roundabout, Axon Guidance Receptor, Homolog 3 Gene - Roundabout, Drosophila, Homolog of, 3 Gene - Scoliosis Gene