Sphingosine 1-Phosphate

**Semantic type:** Organic Chemical

**Definition:** A bioactive sphingolipid comprised of a sphingosine with a phosphate group attached to the carbon at position 1. Sphingosine 1-phosphate (S1P) binds to G protein-coupled S1P receptors (S1PRs) and initiates signaling pathways involved in the regulation of angiogenesis, the proliferation of skin cells, vascular stability and permeability, and T- and B-cell trafficking.

**Synonyms:** - (2-Amino-3-Hydroxy-Octadec-4-Enoxy)Phosphonic Acid - (2S,3R,4E)-2-Amino-3-Hydroxyoctadec-4-En-1-Yl Dihydrogen Phosphate - (2S,3R,4E)-2-Amino-4-Octadecene-1,3-Diol 1-(Dihydrogen Phosphate) - 4-Octadecene-1,3-Diol, 2-Amino-, 1-(Dihydrogen Phosphate), (2S,3R,4E) - 4-Octadecene-1,3-Diol, 2-Amino-, 1-(Dihydrogen Phosphate), (R-(R*,S*-(E)))- - D-Erythro-Sphingosine 1-Phosphate - S1P - SPHINGOSINE 1-PHOSPHATE - SPP - Sphing-4-Enine 1-Phosphate - Sphingosine 1-Phosphic Acid - Sphingosine-1-Phosphate