3-Nitrotyrosine

**Semantic type:** Amino Acid, Peptide, or Protein

**Definition:** A tyrosine derivative with a nitro group attached to carbon 3 on the phenyl ring that is a product of tyrosine nitration mediated by reactive nitrogen species, including peroxynitrite anion and nitrogen dioxide. 3-nitrotyrosine is a biomarker of cell damage, inflammation, and NO (nitric oxide) production; it is overproduced in many diseases where oxidative stress plays a key role.

**Synonyms:** - 3-Mononitrotyrosine - 3-NITRO-L-TYROSINE - 3-NT - Tyrosine, 3-Nitro-