Tocopherylquinone

**Semantic type:** Pharmacologic Substance|Vitamin

**Definition:** An oxidized form of alpha-tocopherol with potent anticoagulant activity. Although the mechanism of action has not been fully elucidated, dietary supplementation with tocopherylquinone may lead to the inhibition of the vitamin K-dependent gamma-carboxylase (gamma-glutamyl carboxylase). This prevents the carboxylation of glutamyl residues in coagulation factor proteins and inhibits platelet aggregation and clotting.

**Synonyms:** - 2,5-Cyclohexadiene-1,4-Dione, 2-(3-Hydroxy-3,7,11,15-Tetramethylhexadecyl)-3,5,6-Trimethyl-, (3R-(3R*,7R*,11R*))- - 2-(3-Hydroxy-3,7,11,15-Tetramethylhexadecyl)-3,5,6-Trimethyl-p-Benzoquinone - Alpha-TQ - Alpha-Tocopherol Quinone - Alpha-Tocopherolquinone - Alpha-Tocopheroquinone - Alpha-Tocoquinone - TOCOQUINONE - TQ - Tocoquinone - VEQ - Vitamin E Quinone - p-Benzoquinone, 2-(3-Hydroxy-3,7,11,15-Tetramethylhexadecyl)-3,5,6-Trimethyl-