24,25-Dihydroxycholecalciferol

**Semantic type:** Vitamin

**Definition:** A vitamin D derivative that is produced by the conversion of calcifediol by 1,25-dihydroxyvitamin D3 24-hydroxylase (CYP24A1). 24,25-dihydroxycholecalciferol is a marker for calcifediol catabolism because it is the major metabolite of calcifediol, and its urine levels are increased in certain diseases, such as chronic kidney disease (CKD).

**Synonyms:** - (3beta,5Z,7E)-9,10-Secocholesta-5,7,10(19)-Triene-3,24,25-Triol - 24,25(OH)(2)D - 24,25(OH)2 D3 - 24,25-DIHYDROXYCHOLECALCIFEROL - 24,25-Dihydroxyvitamin D - 24,25-Dihydroxyvitamin D 3 - 24,25-Dihydroxyvitamin D3 - 24,25-Hydroxy Vitamin D3 - 9,10-Secocholesta-5,7,10(19)-Triene-3,24,25-Triol, (3-beta,5Z,7E)-