C2 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human C2 wild-type allele is located in the vicinity of 6p21.3 and is approximately 48 kb in length. This allele, which encodes complement C2 protein, plays a role in proteolysis and complement activation. Mutation of the gene is associated with C2 deficiency and increased susceptibility for age-related macular degeneration.

**Synonyms:** - ARMD14 - CO2 - Complement Component 2 wt Allele