MICA wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human MICA wild-type allele is located in the vicinity of 6p21.3 and is approximately 16 kb in length. This allele, which encodes MHC class I polypeptide-related sequence A protein, is involved in natural killer cell inhibition. Variation of the gene may be associated with increased susceptibility to psoriasis 1 and psoriatic arthritis.

**Synonyms:** - MHC Class I Polypeptide-Related Sequence A wt Allele - MIC-A - Major Histocompatibility Class I Chain-Related Gene A - PERB11.1