KRT8 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human KRT8 wild-type allele is located in the vicinity of 12q13 and is approximately 53 kb in length. This allele, which encodes keratin, type II cytoskeletal 8 protein, plays a role in the structure of striated muscle and simple epithelia. Mutation of the gene is associated with cryptogenic cirrhosis.

**Synonyms:** - CARD2 - CK-8 - CK8 - CYK8 - K2C8 - K8 - KO - Keratin 8 wt Allele - Keratin 8, Type II Gene