ADRB3 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human ADRB3 wild-type allele is located in the vicinity of 8p11.23 and is approximately 4 kb in length. This allele, which encodes beta-3 adrenergic receptor protein, is involved in catecholamine-dependent G protein-coupled receptor signaling. Mutation and variation in the gene is associated with increased susceptibility to obesity.

**Synonyms:** - ADRB3R - Adrenergic, Beta-3-, Receptor Gene - Adrenoceptor Beta 3 wt Allele - B3AR - BETA3AR