YWHAE/FAM22 Fusion Gene

**Semantic type:** Gene or Genome

**Definition:** A fusion gene that results from a chromosomal translocation t(10;17)(q22;p13) which fuses exon 5 the YWHAE gene with exon 2 of the FAM22A (NUTM2A), FAM22B (NUTM2B), or FAM22E (NUTM2E) gene. These fusions are associated with high grade endometrial stromal sarcomas and clear cell sarcomas of the kidney.

**Synonyms:** - YWHAE-FAM22 Fusion Gene - YWHAE-FAM22A-B-E Fusion Gene - YWHAE-NUTM2 Fusion Gene - YWHAE-NUTM2A-B-E Fusion Gene - YWHAE/FAM22A-B-E Fusion Gene - YWHAE/NUTM2 Fusion Gene - YWHAE/NUTM2A-B-E Fusion Gene - YWHAE::FAM22 Fusion Gene - YWHAE::NUTM2 Fusion Gene - YWHAE::NUTM2A-B-E Fusion Gene - YWHAE::NUTM2A/B/E Fusion Gene