Uterine Corpus Malignant PEComa

**Semantic type:** Neoplastic Process

**Definition:** A malignant neoplasm with perivascular epithelioid cell differentiation arising from the uterine corpus. The neoplasm is usually a large size, and charcaterized by the presence of marked nuclear atypia, pleomorphism, increased mitotic activity, necrosis, and infiltrative margins. The most common metastatic sites are lungs, lymph nodes, and bone. Patients present with a pelvic mass or abnormal bleeding.

**Synonyms:** - Malignant Uterine Corpus PEComa - Malignant Uterine Corpus Perivascular Epithelioid Cell Tumor - Uterine Corpus Malignant Perivascular Epithelioid Cell Tumor