Venlafaxine

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** A synthetic phenethylamine bicyclic derivative with antidepressant activity. Venlafaxine and its active metabolite, O-desmethylvenlafaxine (ODV), are potent inhibitors of neuronal serotonin and norepinephrine reuptake and weak dopamine reuptake inhibitors. This agent may reduce hormone-related vasomotor symptoms. (NCI04)

**Synonyms:** - VENLAFAXINE - venlafaxine