Reticuloendothelial System

**Semantic type:** Body System

**Definition:** A network of phagocytic cells, primarily monocytes and macrophages, located in the connective tissue of the bone marrow, spleen, and liver that are involved in the clearance of bacteria, toxins, exogenous antigens, and immune complexes from the blood and tissues, as well as cytotoxicity against tumor cells.

**Synonyms:** - RE System - Reticuloendothelial system, NOS - reticuloendothelial system