PCSK1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human PCSK1 wild-type allele is located within 5q15-q21 and is approximately 44 kb in length. This allele, which encodes neuroendocrine convertase 1 protein, is involved in the activation of neuropeptides and protein hormones. Mutation of the gene is associated with proprotein convertase 1/3 deficiency and increased susceptibility to obesity.

**Synonyms:** - BMIQ12 - NEC1 - PC1 - PC3 - Proprotein Convertase Subtilisin/Kexin Type 1 wt Allele - SPC3