TIA1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human TIA1 wild-type allele is located in the vicinity of 2p13 and is approximately 39 kb in length. This allele, which encodes nucleolysin TIA-1 isoform p40, plays a role in both RNA binding and splicing. Mutation of the gene is associated with Welander distal myopathy.

**Synonyms:** - P40-TIA-1 (Containing P15-TIA-1) Gene - TIA-1 - TIA1 Cytotoxic Granule-Associated RNA Binding Protein wt Allele - TIA1 Cytotoxic Granule-Associated RNA-Binding Protein Gene - WDM