GAIA Level 4 Major Internal Structural Defect

**Semantic type:** Classification

**Definition:** GAIA Level 4 Major Internal Structural Defect is defined by three criteria: first, the defects are prenatal in origin; second, the defect(s) affect (or have the propensity to affect) the health, survival, or physical or cognitive functioning of the individual; third, at least one of the following requirements must be met: a) Alterations in the internal anatomy that are present at the time of live birth, and that persist beyond the immediate peripartum period unless surgically repaired; OR b) Alterations in the internal anatomy that are present at the time of the stillbirth or of the spontaneous or therapeutic abortion; fourth, at least one of the following requirements must be met: a) Documented confirmation in the medical record that the anomaly was present at the time of live birth or at the time of fetal demise, and that the anomaly was diagnosed by a trained maternal or a child health care provider who has minimal experience diagnosing congenital anomalies; OR b) Confirmed by claims data (ICD-9/ICD-10 diagnoses).

**Synonyms:** - Global Alignment of Immunization safety Assessment in pregnancy Level 4 Major Internal Structural Defect - Level 4 Major Internal Structural Defect