Interferon-Related DNA Damage Resistance Gene Signature

**Semantic type:** Functional Concept

**Definition:** An experimental therapy-predictive system used to assess if patient's tumor may be resistant to chemotherapy. This system is based on the expression profile of a panel of genes that are associated with both interferon signaling pathways and resistance to radiation-induced DNA damage.

**Synonyms:** - IFN-Related DNA Damage Resistance Signature - IRDS