Selective Estrogen Receptor Degrader LSZ102

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** An selective estrogen receptor (ER) degrader (SERD), with potential antineoplastic activity. Upon administration of LSZ102, this agent binds to the ER and induces the degradation of the receptor. This prevents ER activation and ER-mediated signaling, and inhibits the growth and survival of ER-expressing cancer cells.

**Synonyms:** - LSZ 102 - LSZ-102 - LSZ102 - SERD LSZ 102 - SERD LSZ102