Peripheral Zone of Prostate

**Semantic type:** Body Location or Region

**Definition:** The region of the prostate that is located most superficial and posterior as compared to the other prostate zones. It is located closest to the rectum, and is easily palpated on digital rectal exam. This zone of the prostate surrounds the distal urethra, and is the zone of origin for the vast majority of prostatic cancers.

**Synonyms:** - Peripheral Zone - Peripheral zone