Generalized Arterial Calcification of Infancy 1

**Semantic type:** Disease or Syndrome

**Definition:** An autosomal recessive genetic disorder caused by mutations in the ENPP1 gene, encoding ectonucleotide pyrophosphatase/phosphodiesterase family member 1. The condition is characterized by calcification and narrowing of medium- and large-sized arteries, resulting in cardiovascular complications.

**Synonyms:** - GACI1