3-Hydroxy-3-Methylglutaryl-Coenzyme A

**Semantic type:** Nucleic Acid, Nucleoside, or Nucleotide

**Definition:** An intermediate for the synthesis of mevalonic acid, ketone bodies and cholesterol and a metabolic product for leucine; it can be formed de novo from acetyl coenzyme A (CoA) and acetoacetyl CoA by HMG-CoA (3-Hydroxy-3-Methylglutaryl-Coenzyme A) synthase.

**Synonyms:** - (3S)-3-Hydroxy-3-Methylglutaryl-CoA - (S)-3-Hydroxy-3-Methylglutaryl-Coenzyme A - 3-Hydroxy-3-Methylglutaryl-CoA - HMG-CoA - HMG-Coenzyme A - Hydroxymethylglutaroyl Coenzyme A - Hydroxymethylglutaryl-CoA - S-(Hydrogen 3-Hydroxy-3-Methylglutaryl)Coenzyme A - S-(Hydrogen 3-Hydroxy-3-Methylpentanedioate) Coenzyme A