Leukotriene E4

**Semantic type:** Organic Chemical

**Definition:** The final and most stable product of the pathway where 5-lipoxygenase converts arachidonic acid to cysteinyl leukotrienes, with inflammatory activity. Because of its inherent stability, leukotriene E4 is used as a marker for leukotriene production.

**Synonyms:** - (5S,6R,7E,9E,11Z,14Z)-6-(2-Amino-2-Carboxyethyl)Sulfanyl-5-Hydroxyicosa-7,9,11,14-Tetraenoic Acid - (5S-(5R*,6S*(S*),7E,9E,11Z,14Z))-6-((2-Amino-2-Carboxyethyl)Thio)-5-Hydroxy-7,9,11,14-Eicosatetraenoic Acid - (7E,9E,11Z,14Z)-(5S,6R)-6-(Cystein-S-yl)-5-Hydroxyeicosa-7,9,11,14-Tetraenoate - (7E,9E,11Z,14Z)-(5S,6R)-6-(Cystein-S-yl)-5-Hydroxyicosa-7,9,11,14-Tetraenoate - 5S-Hydroxy,6R-(S-Cysteinyl),7E,9E,11Z,14Z-Eicosatetraenoic Acid - 7,9,11,14-Eicosatetraenoic Acid, 6-((2-Amino-2-Carboxyethyl)Thio)-5-Hydroxy-, (5S-(5R*,6S*(S*),7E,9E,11Z,14Z))- - LEUKOTRIENE E4 - LTE4 - Leukotriene E(4) - S-{(1R,2E,4E,6Z,9Z)-1-[(1S)-4-Carboxy-1-Hydroxybutyl]Pentadeca-2,4,6,9-Tetraen-1-yl}-L-Cysteine