Neopterin

**Semantic type:** Organic Chemical

**Definition:** A pteridine that is a metabolite of guanine triphosphate (GTP) and a precursor for biopterin. Neopterin is released from interferon-gamma (IFNg) stimulated macrophages and dendritic cells (DCs); therefore, urine or serum levels may be used as a marker of immune system activation.

**Synonyms:** - 2-Amino-6-(1,2,3-Trihydroxypropyl)-4(3H)-Pteridinone - 4(1H)-Pteridinone, 2-Amino-6-(1,2,3-Trihydroxypropyl)- - NEOPTERIN