Exfoliation Syndrome

**Semantic type:** Disease or Syndrome

**Definition:** An autosomal dominant disorder caused by mutations in the LOXL1 gene, encoding lysyl oxidase homolog 1. The condition is characterized by abnormal fibrillar extracellular material in anterior segment tissues, and may lead to glaucoma.

**Synonyms:** - Exfoliation Glaucoma - XFG - XFS