Supratentorial Ependymoma, ZFTA-RELA Fusion-Positive

**Semantic type:** Neoplastic Process

**Definition:** A supratentorial ependymoma characterized by a gene fusion involving ZFTA and RELA genes. It accounts for the majority of supratentorial ependymomas in children. It has an unfavorable outcome when compared to other ependymoma subtypes.

**Synonyms:** - Ependymoma, RELA Fusion-Positive - Ependymoma, RELA fusion-positive - Ependymoma, ZFTA-RELA Fusion-Positive - Supratentorial Ependymoma, RELA Fusion-Positive - Supratentorial Ependymoma, ZFTA::RELA Fusion-Positive