Medulloblastoma, SHH-Activated

**Semantic type:** Neoplastic Process

**Definition:** A molecular subtype of medulloblastoma associated with activation of the sonic hedgehog (SHH) pathway. TP53 mutations may be present or absent. Patients in this group are young children and adults. Overall survival is variable and depends on the presence or absence of metastatic disease, histology, and the age at diagnosis.

**Synonyms:** - SHH-Activated