Secondary Parathyroid Hormone Resistance

**Semantic type:** Finding

**Definition:** Parathyroid hormone (PTH) resistance caused by vitamin D deficiency and characterized by clinically increased PTH concentrations with relative hyperphosphatemia. The diagnosis can be confirmed by finding of a normal cyclic adenosine monophosphate (cAMP) response to PTH infusion, but deficient phosphaturic response, indicating a defect distal to cAMP generation in renal cells.

**Synonyms:** - Acquired Parathyroid Hormone Resistance - Acquired Parathyroid Hormone Resistance - Pseudohypoparathyroidism, Type 2 - Pseudohypoparathyroidism, Type 2