ARHGAP32 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human ARHGAP32 wild-type allele is located in the vicinity of 11q24.3 and is approximately 314 kb in length. This allele, which encodes Rho GTPase-activating protein 32, plays a role in the modulation of both NMDA receptor signaling and small GTPase activity. Deletion of the chromosomal region containing the gene is associated with a subset of Jacobsen syndrome patients that exhibit autism spectrum disorder.

**Synonyms:** - GC-GAP - GRIT - KIAA0712 - MGC1892 - PX-RICS - RICS - Rho GTPase Activating Protein 32 wt Allele - p200RhoGAP - p250GAP