WWOX wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human WWOX wild-type allele is located in the vicinity of 16q23 and is approximately 1113 kb in length. This allele, which encodes WW domain-containing oxidoreductase protein, is involved in tumor suppression, apoptosis and oxidation/reduction. Mutation of the gene is associated with early infantile epileptic encephalopathy 28, somatic esophageal squamous cell carcinoma, and autosomal recessive spinocerebellar ataxia 12.

**Synonyms:** - D16S432E - EIEE28 - FOR - FRA16D - HHCMA56 - PRO0128 - SCAR12 - SDR41C1 - Short Chain Dehydrogenase/Reductase Family 41C, Member 1 Gene - WOX1 - WW Domain Containing Oxidoreductase wt Allele