SCN5A wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human SCN5A wild-type allele is located in the vicinity of 3p21 and is approximately 102 kb in length. This allele, which encodes sodium channel protein type 5 subunit alpha protein, plays a role in voltage-dependent sodium transport. Mutation of the gene is associated with long QT syndrome-3, sick sinus syndrome 1, Brugada syndrome 1, familial atrial fibrillation 10, familial ventricular fibrillation 1, dialated cardiomyopathy 1E, progressive heart block type 1A and non-progressive heart block.

**Synonyms:** - CDCD2 - CMD1E - CMPD2 - HB1 - HB2 - HBBD - HH1 - ICCD - IVF - LQT3 - Nav1.5 - PFHB1 - SSS1 - Sodium Channel, Voltage Gated, Type V Alpha Subunit Gene - Sodium Channel, Voltage-Gated, Type V, Alpha (Long QT Syndrome 3) Gene - Sodium Channel, Voltage-Gated, Type V, Alpha Subunit Gene - Sodium Voltage-Gated Channel Alpha Subunit 5 wt Allele - VF1