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C1317Level 5

Bupropion Hydrochloride

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** The hydrochloride salt of the aminoketone bupropion, with antidepressant activity and for potential use in promoting smoking cessation and improving sexual desire. Bupropion is a weak blocker of the neuronal uptake of serotonin, dopamine and norepinephrine and is a central nicotinic acetylcholine receptor antagonist.

**Synonyms:** - (+-)-1-(3-Chlorophenyl)-2-[(1,1-dimethylethyl)amino]-1-propanone Hydrochloride - Amfebutamone - BUPROPION HYDROCHLORIDE - BW 323U66 - Wellbutrin

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