Virus-specific Cytotoxic T-lymphocytes

**Semantic type:** Cell|Pharmacologic Substance

**Definition:** A population of cytotoxic T-lymphocytes (CTLs) specifically reactive to one or more pre-selected viruses, with potential antiviral activity. Upon infusion, after an allogeneic hematopoietic cell transplant (HCT) or in other immunodeficient states, these CTLs help reconstitute viral-specific CTL responses and kill virally infected cells, thereby inhibiting viral infection in immunocompromised patients.

**Synonyms:** - Virus-specific CTLs