Acute Megakaryoblastic Leukemia with CBFA2T3-GLIS2

**Semantic type:** Neoplastic Process

**Definition:** A non-Down syndrome acute megakaryoblastic leukemia that occurs in children. It is associated with CBFA2T3-GLIS2 chimeric oncogene and has an unfavorable prognosis.

**Synonyms:** - Acute Megakaryoblastic Leukemia with CBFA2T3::GLIS2 - Acute Megakaryoblastic Leukemia with inv(16)(p13.3q24.3); CBFA2T3-GLIS2 - Acute Megakaryoblastic Leukemia with inv(16)(p13.3q24.3); CBFA2T3::GLIS2 - Acute Myeloid Leukemia with inv(16)(p13.3q24.3); CBFA2T3-GLIS2 - Acute Myeloid Leukemia with inv(16)(p13.3q24.3); CBFA2T3::GLIS2