HPV-Mediated (p16-Positive) Oropharyngeal Cancer pT4 TNM Finding v8

**Semantic type:** Finding

**Definition:** HPV-mediated (p16-positive) oropharyngeal cancer with moderately advanced local disease. Tumor invades the larynx, extrinsic muscle of tongue, medial pterygoid, hard palate, or mandible or beyond. Mucosal extension to lingual surface of epiglottis from primary tumors of the base of the tongue and vallecula does not constitute invasion of the larynx. (from AJCC 8th Ed.)

**Synonyms:** - HPV-Mediated (p16-Positive) Oropharyngeal Carcinoma pT4 TNM Finding v8