RGD Motif

**Semantic type:** Amino Acid Sequence

**Definition:** A consensus tripeptide that is recognized by and for binding to proteins of the integrin family, including many cell adhesion molecules. The one-letter codes for arginine - glycine - aspartic acid. This motif can be found in proteins of the extracellular matrix and it is recognized by different members of the integrin family. The structure of the tenth type III module of fibronectin has shown that the RGD motif lies on a flexible loop.

**Synonyms:** - Arginine-Glycine-Aspartic Acid Cell Adhesion Domain - RGD - RGD Cell Adhesion Domain - RGD Domain - RGD Peptide - RGD Tripeptide Sequence