Unmethylated MGMT Gene Promoter

**Semantic type:** Laboratory or Test Result

**Definition:** A genetic finding indicating the absence of DNA methylation in the promoter region of the MGMT gene. This finding is associated with a poor prognosis in patients with glioblastoma.

**Synonyms:** - Absent - MGMT Gene Promoter Methylation Negative - Negative - Unmethylated MGMT Promoter - Unmethylated MGMT Promoter - Unmethylated Methylguanine-DNA Methyltransferase Gene Promoter - Unmethylated O-6-Methylguanine-DNA Methyltransferase Gene Promoter