Oropharyngeal (p16-Negative) and Hypopharyngeal Cancer TNM Finding v8

**Semantic type:** Finding

**Definition:** A finding about one or more characteristics of p16-negative oropharyngeal and hypopharyngeal cancer, following the rules of the TNM AJCC v8 classification system. This staging system applies to p16-negative squamous cell carcinomas of the oropharynx, oropharyngeal cancers without p16 immunostaining performed, and all cancers of the hypopharynx. Minor salivary gland cancers and neuroendocrine carcinomas of the oropharynx and hypopharynx are included in this classification. Oropharyngeal cancers which are p16-positive are staged according to the classification for p16-positive oropharyngeal cancers. (from AJCC 8th Ed.)

**Synonyms:** - Oropharyngeal (p16-Negative) and Hypopharyngeal Carcinoma TNM Finding v8