PDZ Domain

**Semantic type:** Amino Acid Sequence

**Definition:** A globular protein domain of 80 to 90 amino acids comprising six beta-strands and two alpha-helices that plays a role in anchoring receptor proteins in the membrane to cytoskeletal components.

**Synonyms:** - DHR Domain - Discs-Large Homologous Region - GLGF Domain - Gly-Leu-Gly-Phe Domain - Glycine-Leucine-Glycine-Phenylalanine Domain - PSD95, Dlg1, Zo-1 Domain