AKR1B1 wt Allele

**Semantic type:** Gene or Genome

**Definition:** Human AKR1B1 wild-type allele is located in the vicinity of 7q33 and is approximately 17 kb in length. This allele, which encodes aldose reductase protein, is involved in the metabolism of glucose, toxic aldehydes and steroids. This gene is associated with the development of diabetic complications.

**Synonyms:** - ADR - ALDR1 - ALR2 - AR - Aldo-Keto Reductase Family 1 Member B wt Allele - Aldo-Keto Reductase Family 1, Member B1 (Aldose Reductase) Gene - Aldo-Keto Reductase Family 1, Member B1 Gene