Ametantrone

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** A topoisomerase II inhibitor of the anthrapyrazole family that causes covalent cross-links in DNA of tumor cells.

**Synonyms:** - 1,4-bis[[2-[(2-Hydroxyethyl)amino]ethyl]amino]9,10-anthracenedione - 9, 10-Anthracenedione, 1, 4-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]- - AMETANTRONE