Azimexon

**Semantic type:** Organic Chemical|Pharmacologic Substance

**Definition:** Azimexon (2-cyanaziridinyl-2-carbamoyl-aziridinyl-1-propane) is a derivative of 2-cyanaziridine. Immunostimulant which shows therapeutic effects in tumor models and experimental infections in vitro, enhancing T lymphocyte transformation and phagocytosis. The mode of action of azimexon is unknown. It has been suggested that azimexon may alkylate DNA. In cancer patients it increases leukocytosis, blood active T rosettes, T4/T8 ratio, and is used as an adjuvant to chemotherapy in the treatment of melanoma and myeloma.

**Synonyms:** - 2-Aziridinecarboxamide, 1-[1-(2-cyano-1-aziridinyl)-1-methylethyl] - 2-Cyanaziridinyl-2-carbamoyl-aziridinyl-1-propane - AZ - AZIMEXON - Azimexone - BM 12.531 - BM12531