Luminal B Prostate Carcinoma

**Semantic type:** Neoplastic Process

**Definition:** Prostate carcinoma associated with increased androgen receptor expression and signaling (androgen activity pathway), increased luminal markers, and a higher proliferation score than the luminal A prostate carcinoma. Patients with luminal B prostate carcinoma have the poorest prognosis but respond better to postoperative androgen deprivation therapy compared to patients with non-luminal B prostate carcinoma.

**Synonyms:** - Luminal B Prostate Cancer