BH3 Domain

**Semantic type:** Amino Acid Sequence

**Definition:** The alpha-helical BH3 domain (9 amino acids) represents a minimal death domain and is essential for the activity of pro-apoptotic members of the bcl-2 family. Some of these proteins only contain a BH3 domain.

**Synonyms:** - BH-3 - BH3 - Bcl-2 Homology Domain 3 - Bcl-2 Homology Domain-3